Arsenal Women v Zurich: Gunners reach Champions League century
The Gunners are looking to build on their 5-1 victory against current holders Lyon from the first round of fixtures in Group C, while their opponents will try to bounce back from a 2-0 defeat to Juventus.
A strong start sees them already top of their group, but manager Jonas Eidevall was quick to squash claims that they will win the whole tournament.
Arsenal still have to play Zurich, as well as Juventus, in order to advance to the last 16.
"It's game by game. We have to do our part, prepare to be as fit as possible, execute as well as possible. Then we'll have to see where that leads us in the league table," said Eidevall.
"For us to play one really good game away to Lyon and get a great result and to start speaking about us winning the whole competition, I don't like that. I don't think that's humble enough. That's not where we come from."
Rafaelle Souza (31) and Leah Williamson (25) will be unavailable due to injury - but Lina Hurtig (27), Laura Wienrroither (23) and Lia Walti (29) are all expected to return to the squad.
The two sides haven't met for 14 years, with the last match ending with Arsenal winning 7-2.
Ahead of the fixture on Thursday, Zurich manager Inka Grings described it as a "David and Goliath" match.
"With Arsenal, the next heavyweight awaits us in a fantastic stadium. They showed against the title defenders of Olympique Lyonnais what outstanding players they have in their ranks.
"The game is a showdown between David and Goliath. We will do everything we can to stress Arsenal, for this, we have to leave our heart on the pitch."
Player to watch: Beth Mead (27) already has three goals and two assists in the Women's Super League this season - as well as scoring twice and providing once against Lyon - and will look to continue her superb form in 2022 against Zurich.
Hot stat: This will be Arsenal's 100th game in the competition.
