Five-star Makinson drives England into Rugby League World Cup semis
The tournament hosts will play the winners of the quarter-final between Tonga and Samoa, scheduled for Sunday, at Arsenal's Emirates Stadium in London on November 12.
Reigning champions Australia despatched Lebanon 42-4 on Friday and face the winners of the quarter-final between 2008 champs New Zealand and three-time semi-finalists Fiji 24 hours earlier at Elland Road in Leeds.
England enjoyed a dream start in Wigan, scoring seven tries in the opening 27 minutes, including three for Makinson as they shot into a lead they never looked like surrendering.
"I thought the first half was faultless, second half it was a bit scrappy but overall, to beat a team like Papua New Guinea. I'm really impressed," England coach Shaun Wane told BBC.
"Makinson has done it for years and years. He's worked hard and fair play to him. He's done it for St Helens and England and Great Britain. Outstanding."
Looking ahead to next weekend, Wane added: "Tonga and Samoa are great teams, we know it will be a massive challenge (in the semi-finals). We will give them respect that they deserve.
"We will keep improving every time we train. That's the way we do things and hopefully next week we will improve."
Tom Burgess was the first on the scoresheet, bulldozing his way over after six minutes. Makinson converted and then went over for England's second four-pointer just minutes later.
Star Newcastle Knights winger Dom Young continued his fine try-scoring run with his ninth of the competition before Makinson grabbed his double to make it 20 points in 20 minutes in a remarkable start by England.
Playmaker George Williams was next on the scoresheet as a shell-shocked PNG struggled with England's direct midfield charges and astute kicking game.
Kallum Watkins grabbed a try of his own before Makinson sealed his hat-trick to leave PNG 38-0 down at half-time.
The Kumuls did not roll over, firming up their defence, albeit far too late to mae it a real contest.
After 30 minutes of resistance from PNG, Makinson finally broke the deadlock, sliding over for his fourth try on 58 minutes.
PNG eventually got on the scoreboard with 10 minutes to play, Jimmy Ngutlik sliding in to touch down a great Alex Johnston kick that caught Young napping in the corner. Rhyse Martin converted.
Fittingly, Makinson had the final word, crossing for his fifth try and a personal tally of 30 points.
"I'm disappointed that I didn't get on the scoresheet but I'm happy for my winger who got five," joked England centre Herbie Farnworth of Makinson.
"I think the opening 30 minutes for us sets the tone for how we want to play in this World Cup."
