Drag down or refresh for latest updates
Live updates
09:07 BST - The first fixture today sees Chelsea travel to West Ham's London Stadium, where they have struggled in recent years. The Blues have only won twice away to the Hammers since their stadium switch.
Manager Enzo Maresca has put his faith in Nicolas Jackson to help end that poor run, who he sees as Chelsea's main number nine going forward despite the emergence of Christopher Nkunku.
08:08 BST - Plenty of top stars are set to miss this weekend's action, including Arsenal captain Martin Odegaard and potentially Liverpool goalkeeper Alisson.
See our full list of who's missing here.
07:20 BST - Good morning and welcome to our Football Tracker, where you'll be able to get all the major news and updates across this weekend's Premier League matches!
Up first today is West Ham v Chelsea at 12:30, followed by six fixtures at 15:00 before Crystal Palace v Manchester United rounds off the day's action at 17:30.