Manchester City have to travel to Tottenham Hotspur before a relatively easy final four games, while Arsenal have to face Manchester United and their north London rivals - both away from home.
While their title credentials are very slim, Spurs have a very difficult final five games including three of their direct competitors.
Chelsea find themselves in a similar situation in terms of their title chances - but their last fixtures are certainly very favourable if they do find themselves pushing for the trophy or even for a top four spot.
Below are the last five league fixtures for those expected to battle for the Premier League trophy. Will Manchester City win it for the fourth season in a row?
Manchester City
Matchday 34 - Spurs (A)
Matchday 35 - Nottingham Forest (A)
Matchday 36 - Wolves (H)
Matchday 37 - Fulham (A)
Matchday 38 - West Ham (H) (last game of the season)
Liverpool
Matchday 34 - Fulham (A)
Matchday 35 - West Ham (A)
Matchday 36 - Spurs (H)
Matchday 37 - Aston Villa (A)
Matchday 38 - Wolves (H)
Arsenal
Matchday 34 - Wolves (A)
Matchday 35 - Spurs (A)
Matchday 36 - Bournemouth (H)
Matchday 37 - Manchester United (A)
Matchday 38 - Everton (H)
Manchester United
Matchday 34 - Newcastle (H)
Matchday 35 - Burnley (H)
Matchday 36 - Crystal Palace (A)
Matchday 37 - Arsenal (H)
Matchday 38 - Brighton (A)
Newcastle
Matchday 34 - Manchester United (A)
Matchday 35 - Sheffield United (H)
Matchday 36 - Burnley (A)
Matchday 37 - Brighton (H)
Matchday 38 - Brentford (A)
Chelsea
Matchday 34 - Brighton (A)
Matchday 35 - Aston Villa (A)
Matchday 36 - West Ham (H)
Matchday 37 - Nottingham Forest (A)
Matchday 38 - Bournemouth (H)
Tottenham Hotspur
Matchday 34 - Manchester City (H)
Matchday 35 - Arsenal (H)
Matchday 36 - Liverpool (A)
Matchday 37 - Burnley (H)
Matchday 38 - Sheffield United (A)
