Who's Missing: Ake unlikely for Man City and Chelsea injuries mount
Elsewhere, Nottingham Forest's injury list remains as long as ever, Spurs have lost their captain for the remainder of the season and Arsenal are still without key defender William Saliba.
Take a look at who's out and who may still feature in the upcoming latest round of Premier League fixtures.
Leeds v Newcastle
WILL NOT PLAY
Leeds:
Tyler Adams (Thigh Injury)
Liam Cooper (Muscle Injury)
Stuart Dallas (Broken Leg)
Luis Sinisterra (Thigh Injury)
Newcastle:
Ryan Fraser (Lacking Match Fitness)
Emil Krafth (Knee Injury)
Jamaal Lascelles (Calf Injury)
QUESTIONABLE
Sean Longstaff (Foot Injury)
Aston Villa v Tottenham
WILL NOT PLAY
Aston Villa:
Jed Steer (Muscle Injury)
Tottenham:
Rodrigo Bentancur (Knee Injury)
Hugo Lloris (Muscle Injury)
Ryan Sessegnon (Thigh Injury)
QUESTIONABLE
Matty Cash (Calf Injury)
Chelsea v Nottingham Forest
WILL NOT PLAY
Chelsea:
Marcus Bettinelli (Injury)
Armando Broja (Knee Injury)
Ben Chilwell (Muscle Injury)
Marc Cucurella (Thigh Injury)
Reece James (Hamstring Injury)
Kalidou Koulibaly (Thigh Injury)
Mason Mount (Pelvis Injury)
Nottingham Forest:
Giulian Biancone (Knee Injury)
Dean Henderson (Thigh Injury)
Scott McKenna (Shoulder Injury)
Omar Richards (Calf Injury)
Neco Williams (Concussion)
Chris Wood (Thigh Injury)
QUESTIONABLE
Wesley Fofana (Muscle Injury)
Jack Colback (Head Injury)
Gustavo Scarpa (Knee Injury)
Crystal Palace v Bournemouth
WILL NOT PLAY
Crystal Palace:
Naouirou Ahamada (Ankle Injury)
Nathan Ferguson (Lacking Match Fitness)
James McArthur (Hamstring Injury)
James Tomkins (Muscle Injury)
Bournemouth:
Ryan Fredericks (Calf Injury)
Kieffer Moore (Head Injury)
Junior Stanislas (Injury)
Marcus Tavernier (Thigh Injury)
Hames Traore (Ankle Injury)
Manchester United v Wolves
WILL NOT PLAY
Manchester United:
Mason Greenwood (Inactive)
Tom Heaton (Ankle Injury)
Phil Jones (Knee Injury)
Lisandro Martinez (Muscle Injury)
Scott McTominay (Health problems)
Donny van de Beek (Knee Injury)
Raphael Varane (Muscle Injury)
Wolves:
Chiquinho (Knee Injury)
Sasa Kalajdzic (Knee Injury)
Boubacar Traore (Lacking Match Fitness)
Southampton v Fulham
WILL NOT PLAY
Southampton:
Juan Larios (Muscle Injury)
Romain Perraud (Knock)
Mohammed Salisu (Muscle Injury)
Fulham:
Layvin Kurzawa (Knee Injury)
Andreas Pereira (Ankle Injury)
Tim Ream (Arm Injury)
QUESTIONABLE
Armel Bella-Kotchap (Injury)
Valentino Livramento (Lacking Match Fitness)
Brentford v West Ham
WILL NOT PLAY
Brentford:
Pontus Jansson (Thigh Injury)
Keane Lewis-Potter (Knee Injury)
Christian Norgaard (Knock)
West Ham:
Vladimir Coufal (Thigh Injury)
Gianluca Scamacca (Knee Injury)
QUESTIONABLE
Kurt Zouma (Ankle Injury)
Everton v Manchester City
WILL NOT PLAY
Everton:
Seamus Coleman (Knee Injury)
Ben Godfrey (Groin Injury)
Ruben Vinagre (Calf Injury)
Manchester City:
Nathan Ake (Muscle Injury)
Benjamin Mendy (Suspended)
Arsenal v Brighton
WILL NOT PLAY
Arsenal:
Mohamed Elneny (Knock)
William Saliba (Back Injury)
Takehiro Tomiyasu (Knee Injury)
Brighton:
Adam Lallana (Thigh Injury)
Tariq Lamptey (Knee Injury)
Jeremy Sarmiento (Ankle Injury)
Joel Veltman (Muscle Injury)
Leicester v Liverpool
WILL NOT PLAY
Leicester:
Ryan Bertrand (Knee injury)
Jonny Evans (Calf injury)
James Justin (Achilles tendon rupture)
Liverpool:
Stefan Bajcetic (Abductor muscle tear)
Calvin Ramsay (Knee injury)
