The Three Lions' U21 coach will replace Gareth Southgate, on a temporary basis, ahead of the international tournament that starts next month.
Carsley has been among the England ranks since 2020, initially taking charge of the U20 squad.
The former Everton and Derby County midfielder has been the U21 manager since 2021.
Carsley led his team to U21 Euros glory last summer, beating Spain 1-0 in the final to secure England their first title in the competition since 1984.
His first match in charge of England's senior team will be on Semptember 7th against Ireland.
Carsley managerial career began in 2012, just a year after hanging up his boots.
He took over at Coventry, his last club as a player, as caretaker manager on two occasions, in 2012 and again in 2013.
In 2015, he was named head coach of Brentford - where he was already a member of staff at the time - but was replaced by Dean Smith after five matches in charge.
In 2017, Carsley was named caretaker manager of Birmingham before Steve Cotterill was installed - after becoming his assistant, Carsley left the club in 2018 when Cotterill was sacked.
