Ashanti Airlines and their financial partners Zotus Group were awarded the tender to operate Ghana Airlines out of the capital Accra, which will include several domestic and regional routes as well as flights to London Heathrow and New York.
Heskey, who played for Leicester, Liverpool and Aston Villa as well as England during a stellar career, co-founded the Zotus Group with Manchester-based entrepreneur Davison Simango.
It will be the first time the country has had a national airline following the collapse of Ghana International Airlines in 2010.
The carrier should start operating ahead of the African Games which gets underway on August 4.
"There is a lot of work on-going already to get the airline ready for start-up, we are in the market sourcing aircraft to start our operations with a significant focus on cargo and passenger manifest from the British Government," Heskey said in a statement.
"It is with this support we anticipate a successful business model from the outset."
