Ireland captain Sexton set to miss remainder of the season
Sexton was hurt during the closing stages of the match in Dublin on March 18, which clinched Ireland's first Grand Slam since 2018.
Sexton's provincial team, Leinster, said in a statement on Monday the 37-year-old fly-half would undergo a procedure the following day.
"Johnny Sexton will see a specialist on Tuesday and have a procedure on the groin injury picked up in Ireland's Six Nations game against England, which will likely keep him sidelined for the remainder of the Leinster Rugby season," Leinster said.
It means Sexton, who will retire after the World Cup in France later this year, has probably played his final game for Leinster.
Ireland's opening World Cup warm-up Test is against Italy in Dublin on August 5.
Leinster are chasing a Champions Cup and United Rugby Championship double.
They host Irish rivals Ulster in the Champions Cup round of 16 on Saturday, with the winners facing a home quarter-final against Leicester or Edinburgh a week later.
Leinster are runaway leaders of the URC, and will contest the play-offs next month as clear title favourites.