"No Ronaldo, no problem," will likely be a common headline tonight and tomorrow as the former Manchester United star started the match on the bench.
Ramos started in his captain's place and made (very) good on his chance, bagging a hat-trick.
Pepe, Raphael Guerreiro and Rafael Leao also got in on the scoring for Portugal, while Manuel Akanji got his side's goal.
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Minute-by-minute commentary below...
90+5' The referee blows for the end of today's match.
90+2' 6 - 1 It's in the back of the net! Raphael Guerreiro slips the ball through to Rafael Leao (Portugal), and he darts into the box to unleash a magnificent shot inside the right post. He makes it six.
89' Substitution. Breel Embolo did his best and is replaced by Ardon Jashari (Switzerland).
87' Fernando Santos has decided to make a change. Rafael Leao (Portugal) replaces Bruno Fernandes.
84' Cristiano Ronaldo (Portugal) has a goal ruled out for offside!
81' The referee signals that it is time for a substitution and Ruben Neves (Portugal) comes onto the pitch so that Bernardo Silva can be given a rest.
73' The referee signals a substitution. Cristiano Ronaldo (Portugal) is brought on as a substitute for Joao Felix.
73' Fernando Santos has decided to substitute Otavio and he is replaced by Vitinha (Portugal).
73' Today's match ends for Goncalo Ramos who will be replaced by Ricardo Horta (Portugal).
70' Raphael Guerreiro (Portugal) clips a neat ball into the box in the direction of Bruno Fernandes, but he can't get on the end of the pass.
67' 5 - 1 Goal! Joao Felix gets to the ball, slips Goncalo Ramos (Portugal) into the area and he scores with a delightful chipped finish to make it five.
66' Substitution. Noah Okafor (Switzerland) receives a signal from the referee and is now allowed to enter the pitch as Ruben Vargas walks off.
59' Yellow card. Eray Comert (Switzerland) goes into the book for a bad tackle on his opponent.
58' 4 - 1 Manuel Akanji (Switzerland) collects the ball deep inside the box from a rebound after the corner kick. He beats the keeper with a sharp shot! It's a goal!
55' 4 - 0 GOAL! Raphael Guerreiro (Portugal) runs onto a pass from Goncalo Ramos after great counter attacking play and hits a fine first-time shot into the net from close range.
54' Here is a change. Djibril Sow is going off and Murat Yakin gives the last tactical orders to Haris Seferovic (Switzerland).
54' Denis Zakaria (Switzerland) joins the action as a substitute, replacing Remo Freuler.
51' 3 - 0 Goal - 3:0! Diogo Dalot laid the ball off to Goncalo Ramos (Portugal), who shot from close range into the right side of the goal, leaving the goalkeeper helpless.
46' Murat Yakin has made a change at the break. Eray Comert (Switzerland) has come on in place of Fabian Schar.
46' The referee blows his whistle to signal the start of the second half.
45+4' The match has reached half-time.
43' Fabian Schar (Switzerland) will miss the next game.
43' Fabian Schar (Switzerland) is booked after bringing down an opponent. Cesar Arturo Ramos had an easy-decision to make.
43' Goncalo Ramos (Portugal) runs with the ball towards the keeper and pulls the trigger from close range, but Yann Sommer anticipates his intention and makes an amazing save to stop the shot going into the bottom right corner. Portugal will take a corner kick.
38' Edimilson Fernandes (Switzerland) sends a teasing cross into the area, but Diogo Costa intercepts the ball. Remo Freuler (Switzerland) tries to nod in a rebound. His close-range effort is denied by the goalkeeper, who pulls off a stunning save.
33' 2 - 0 Gooal! Bruno Fernandes takes over corner duties. Pepe (Portugal) gets his head on the ball from the corner and puts it into the left side of the net.
17' 1 - 0 Joao Felix feeds the ball through to Goncalo Ramos (Portugal), who picks up the pass inside the box and quickly sends it into the top left corner! The goalkeeper was helpless.
1' Today's match has just started, enjoy the game!
