Moefana starts at centre with France for New Zealand clash
Les Bleus will also have to do without prop Cyril Baille and flyhalf Romain Ntamack, who are missing out on the tournament through injury.
"We're getting into this match with the best France team," head coach Fabien Galthie told a news conference on Wednesday.
France, who are gunning for a maiden World Cup title, finished their preparations with a convincing 41-17 victory against Australia.
Team:
15-Thomas Ramos, 14-Damian Penaud, 13-Gael Fickou, 12-Yoram Moefana, 11-Gabin Villiere, 10-Matthieu Jalibert, 9-Antoine Dupont (cap), 8-Gregory Alldritt, 7-Charles Ollivon, 6-Francois Cros, 5-Thibaud Flament, 4-Cameron Woki, 3-Uini Atonio, 2-Julien Marchand, 1-Reda Wardi
Replacements: 16-Peato Mauvaka, 17-Jean-Baptiste Gros, 18-Dorian Aldegheri, 19-Romain Taofifenua, 20-Paul Boudehent, 21-Maxime Lucu, 22-Arthur Vincent, 23-Melvyn Jaminet