Substitute Rouzbeh Cheshmi struck from outside the box in the 98th minute, before Ramin Rezaeian added a second to seal victory for Iran, who have now boosted their chances of reaching the knockout stages for the first time in their history.
Read our minute-by-minute updates below.
View the full summary of the match at Flashscore.
90+13' Nothing more will happen in this game as the referee blows for full-time.
90+11' 0 - 2 GOAL! Ramin Rezaeian (Iran) collects a pass and from inside the box he lifts the ball over Danny Ward, who was off his line. What a finish that is! 0:2.
90+8' 0 - 1 Roozbeh Cheshmi (Iran) quickly gets to a rebound. He is not worried how far out he is and slams the ball towards goal. To the amazement of all, it goes all the way into the bottom right corner. He makes it 0:1 with this magnificent strike.
90+5' Alireza Jahanbakhsh (Iran) is literally asking for a yellow card with his behaviour. The referee agrees and books him.
90+5' Ramin Rezaeian (Iran) argues with the referee and is booked for dissent.
87' Forced substitution due to red card. Danny Ward joins the action as a substitute, replacing Aaron Ramsey (Wales).
86’ The ref signals that VAR has overturned that yellow card and upgraded it to a straight red for Wayne Hennessey (Wales). He’s got to go!
86’ It's been a while since that contentious challenge by Wayne Hennessey (Wales), but referee Mario Escobar must have received some information as he makes the VAR signal. He's going to review and it could result in a red card!
85' Wayne Hennessey (Wales) makes a really bad tackle on his opponent and is relieved when the referee only shows him a yellow card.
84' Ben Davies (Wales) receives a low pass just outside the box and unleashes a fine strike towards the roof of the net. Hossein Hosseini pulls off a reflexive save to block his effort. Nice goalkeeping skill, indeed. Now Wales have a corner.
83' Carlos Queiroz decides to make a substitution. Saeid Ezatolahi will be replaced by Ali Karimi (Iran).
78' The substitution is prepared. Roozbeh Cheshmi (Iran) joins the action as a substitute, replacing Ahmad Noorollahi.
77' Substitution. Ethan Ampadu leaves the pitch and is replaced by Joe Allen (Wales).
77' Carlos Queiroz has decided to substitute Ali Gholizadeh and he is replaced by Alireza Jahanbakhsh (Iran).
77' It's time for a substitution. That's the last involvement from Ehsan Hajsafi as he is replaced by Mehdi Torabi (Iran).
73' Saeid Ezatolahi (Iran) fashions a shot from the edge of the box after receiving an accurate pass. Wayne Hennessey makes a stunning save to stop the effort from flying into the bottom left corner. The ball is out of play. Iran will have a chance to score from a corner.
68' The substitution has been made. Karim Ansarifard (Iran) has replaced Sardar Azmoun.
58' Robert Page prepares a substitution. Harry Wilson is replaced by Daniel James (Wales).
58' We are about to witness a substitution. Brennan Johnson (Wales) is replacing Connor Roberts.
53' Sardar Azmoun (Iran) gets to a rebound in front of goal and sends the ball towards the middle of the goal. However, he couldn't beat Wayne Hennessey, who shows off his superb goalkeeping ability by pulling off a great save.
52' Ali Gholizadeh (Iran) fires a rebound from mid-range onto the left post!
52' OFF THE POST! Sardar Azmoun (Iran) drifts into the box to give his teammate support. He receives a fantastic pass and shoots from close range, but it crashes against the right post! It could have been a brilliant goal, unlucky.
46' Referee Mario Escobar blows his whistle to start the second half.
45+5' The referee blows his whistle for half-time, bringing to a close the first 45 minutes of the match.
45+3' Mario Escobar shows a yellow card to Joe Rodon (Wales) for a tough tackle.
17' Here comes the VAR verdict. NO GOAL for Iran due to an offside in the build-up play.
17' The Iran players halt their celebrations as referee Mario Escobar makes the VAR signal to review the goal, most likely to ascertain if there was an offside in the build-up play.
16' 0 - 1 Ali Gholizadeh (Iran) has acres of space after latching on to a precise pass into the box. He doesn't hesitate to unleash a great effort which ends up in the left side of the goal.
12' Kieffer Moore (Wales) wastes a huge opportunity! He receives a precise cross inside the penalty area and releases a quick shot that sails towards the middle of a goal. His effort, however, lacks power and the goalkeeper makes a comfortable save.
1' The first half of this match is about to start.
Pre-match:
Wales starting XI: Hennessey; Mepham, Rodon, B. Davies; Roberts, Ampadu, Ramsey, Wilson, N. Williams, Bale, Moore
Iran starting XI: H. Hosseini; Rezaeian, Pouraliganji, M. Hosseini, Mohammadi; Gholizadeh, Ezatolahi, Nourollahi, Hajisafi; Azmoun, Taremi
Players to watch: Bale’s goal against the USA was his fourth in a major tournament for Wales and means he has scored five times in his last nine games for his country. Meanwhile, Mehdi Taremi’s brace against England moved the Iran striker onto 13 goals for club and country this season, with eight of his nine goalscoring appearances being the first or last of the game.
Hot stat: Wales are unbeaten in their last six games against teams from outside of Europe (W2, D4).
World Cup trivia: Wales’ 64-year gap between their first and second appearances at the World Cup finals is the longest of any nation.
